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Best NBA Bets for April 22, 2025

The NBA Playoffs are officially heating up, and so is the betting action. With momentum swinging in every game, identifying strong trends and riding hot hands has never been more important. Teams are starting to show their true colors, and that means we can capitalize on key matchups and against-the-spread performances.

Yesterday was a perfect 2-0 day for our Hot Streak Picks. Let’s take a quick look at how it all played out:

Detroit Pistons +6 @ New York Knicks – The Pistons pulled off a stunning 100-94 upset, snapping their record-setting 15-game postseason losing streak. Cade Cunningham led the way with 33 points and 12 rebounds, and Dennis Schroder sealed the deal with a clutch three-pointer.

LA Clippers -1.5 at Denver Nuggets – Kawhi Leonard was a force of nature, dropping 39 points on 15-of-19 shooting. The Clippers took a 105-102 win to even the series and delivered big for our bet.

Now let’s ride that momentum into today’s top plays:

🔒 Milwaukee Bucks +4.5 at Indiana Pacers
The Pacers lead the series 1-0, but Milwaukee has a strong ATS trend, covering in 4 of their last 5 against Indiana. Meanwhile, the Pacers are just 3-12 ATS against Eastern Conference teams. We like the Bucks to keep it tight or steal a win.

🔒 LA Lakers -5.5 vs Minnesota Timberwolves
The Timberwolves are up 1-0, but the Lakers are dominant at home—winning 15 of their last 20 at Crypto.com Arena. They’re also 14-6 SU when playing as the favorite. Look for LA to bounce back and cover tonight.

Final Thoughts
These NBA bets are backed by strong trends and favorable matchups, making them worth considering for your wagers. Whether you’re placing bets on FanDuel, DraftKings, PrizePicks, Underdog, Sleeper, or BetMGM, these plays have solid value based on recent performances. As always, bet responsibly and enjoy the action!