2025 NFL Office Pool and Odds for Week 2

Get ready for another thrilling week of football with our in-depth breakdown of the 2025 NFL Week 2 schedule, featuring the latest odds, matchup analysis, and expert predictions. Whether you’re betting against the spread or aiming to win your office pool, this is your go-to source for trusted insights. Each week, we deliver free NFL office pool picks and NFL confidence pool picks to help you make smart choices and gain an edge over the competition. From early kickoffs to primetime showdowns, we’ve got every Week 2 matchup covered—so you can enjoy the action and play to win.
Office Pool Picks
16 – Baltimore Ravens
15 – Buffalo Bills
14 – San Francisco 49ers
13 – Cincinnati Bengals
12 – Los Angeles Rams
11 – Detroit Lions
10 – Arizona Cardinals
09 – Dallas Cowboys
08 – Minnesota Vikings
07 – Denver Broncos
06 – Los Angeles Chargers
05 – Miami Dolphins
04 – Houston Texans
03 – Green Bay Packers
02 – Pittsburgh Steelers
01 – Kansas City Chiefs
Week 2 NFL Schedule & Odds
Thursday, September 11
Washington Commanders vs. Green Bay Packers(-1.5) 48.5
Sunday, September 14
Cleveland Browns vs. Baltimore Ravens(-12.5)44.5
Jacksonville Jaguars vs. Cincinnati Bengals(-5.5)49.5
New York Giants vs. Dallas Cowboys(-4.5)44.5
Chicago Bears vs. Detroit Lions(-4.5) 48.5
New England Patriots vs. Miami Dolphins(-2.5)45.5
San Francisco 49ers(-7)44.5 vs. New Orleans Saints
Buffalo Bills(-8.5) 44.5 vs. New York Jets
Seattle Seahawks vs. Pittsburgh Steelers(-1.5)42.5
Los Angeles Rams(-5.5)45.5 vs. Tennessee Titans
Carolina Panthers vs. Arizona Cardinals(-4.5)46.5
Denver Broncos(-3.5)44.5 vs. Indianapolis Colts
Philadelphia Eagles vs. Kansas City Chiefs(-1.5)45.5
Atlanta Falcons vs. Minnesota Vikings(-4.5)45.5
Monday, September 15
Tampa Bay Buccaneers vs. Houston Texans(-1.5)46.5
Los Angeles Chargers(-3)44.5 vs. Las Vegas Raiders