2025 NFL Office Pool and Odds for Week 4
Get ready for another thrilling week of football with our in-depth breakdown of the 2025 NFL Week 4 schedule, featuring the latest odds, matchup analysis, and expert predictions. Whether you’re betting against the spread or aiming to win your office pool, this is your go-to source for trusted insights. Each week, we deliver free NFL office pool picks and NFL confidence pool picks to help you make smart choices and gain an edge over the competition. From early kickoffs to primetime showdowns, we’ve got every Week 4 matchup covered—so you can enjoy the action and play to win.
Office Pool Picks
16 – Buffalo Bills
15 – Detroit Lions
14 – Houston Texans
13 – Miami Dolphins
12 – Los Angeles Rams
11 – Los Angeles Chargers
10 – San Francisco 49ers
09 – New England Patriots
08 – Arizona Cardinals
07 – Minnesota Vikings
06 – Kansas City Chiefs
05 – Denver Broncos
04 – Washington Commanders
03 – Las Vegas Raiders
02 – Tampa Bay Buccaneers
01 – Dallas Cowboys
Week 4 NFL Schedule & Odds
Thursday, September 25
Seattle Seahawks at Arizona Cardinals(-3.5)
Sunday, September 28
Minnesota Vikings(-3.2) vs. Pittsburgh Steelers
Washington Commanders(-1.1) at Atlanta Falcons
New Orleans Saints at Buffalo Bills(-11.8)
Cleveland Browns at Detroit Lions(-10.7)
Tennessee Titans at Houston Texans(-8.9)
Carolina Panthers at New England Patriots(-4.9)
Los Angeles Chargers(-5.3) at New York Giants
Philadelphia Eagles at Tampa Bay Buccaneers(-0.3)
Indianapolis Colts at Los Angeles Rams(-7.05)
Jacksonville Jaguars at San Francisco 49ers(-5.28)
Baltimore Ravens at Kansas City Chiefs(-3)
Chicago Bears at Las Vegas Raiders(-0.6)
Green Bay Packers at Dallas Cowboys(-0.3)
Monday, September 29
New York Jets at Miami Dolphins(-7.3)
Cincinnati Bengals at Denver Broncos(-2.2)