2025 NFL Office Pool and Odds for Week 16
Get ready for another thrilling week of football with our in-depth breakdown of the 2025 NFL Week 16 schedule, featuring the latest odds, matchup analysis, and expert predictions. Whether you’re betting against the spread or aiming to win your office pool, this is your go-to source for trusted insights. Each week, we deliver free NFL office pool picks and NFL confidence pool picks to help you make smart choices and gain an edge over the competition. From early kickoffs to primetime showdowns, we’ve got every Week 16 matchup covered—so you can enjoy the action and play to win.
Office Pool Picks
16 – Buffalo Bills(-8.8)
15 – Baltimore Ravens(-8.3)
14 – Kansas City Chiefs(-7)
13 – Houston Texans(-6.5)
12 – Denver Broncos(-5.4)
11 – New Orleans Saints(-4.8)
10 – Detroit Lions(-4.7)
09 – Arizona Cardinals(-4.1)
08 – Minnesota Vikings(-3.2)
07 – Tampa Bay Buccaneers(-1.6)
06 – Chicago Bears(-1.4)
05 – San Francisco 49ers(-1.1)
04 – Los Angeles Rams(-1.1)
03 – Washington Commanders(-0.8)
02 – Los Angeles Chargers(-0.8)
01 – Miami Dolphins(-0.3)
Week 16 NFL Schedule & Odds
Thursday, December 18
Los Angeles Rams(-1.1) at Seattle Seahawks
Saturday, December 20
Philadelphia Eagles at Washington Commanders(-0.8)
Green Bay Packers at Chicago Bears(-1.4)
Sunday, December 21
New England Patriots at Baltimore Ravens(-8.3)
Tampa Bay Buccaneers(-1.6) at Carolina Panthers
Buffalo Bills(-8.8) at Cleveland Browns
Los Angeles Chargers(-0.8) at Dallas Cowboys
New York Jets at New Orleans Saints(-4.8)
Minnesota Vikings(-3.2) at New York Giants
Kansas City Chiefs(-7) at Tennessee Titans
Atlanta Falcons at Arizona Cardinals(-4.1)
Jacksonville Jaguars at Denver Broncos(-5.4)
Pittsburgh Steelers at Detroit Lions(-4.7)
Las Vegas Raiders at Houston Texans(-6.5)
Cincinnati Bengals at Miami Dolphins(-0.3)
Monday, December 22
San Francisco 49ers(-1.1) at Indianapolis Colts